Crestor is the brand name of a leading FDA-approved prescription medication for high cholesterol. (The generic name is rosuvastatin.) The drug lowers “bad” cholesterol (or LDL) and triglycerides in the blood while also raising levels of “good” cholesterol (or HDL.). Although the drug is not for everyone, doctors prescribe Crestor as an effective treatment plan for people when a healthy diet and lifestyle are not enough to lower cholesterol.
Cholesterol and Health
The main reason doctors prescribe Crestor for their patients is to reduce the chances of serious medical problems such as stroke, heart attack, and other cardiovascular diseases. Cholesterol is a substance found in the fats of your blood. Your body needs cholesterol for creating new cells. However, if cholesterol is too high in your blood, you are at increased risk of heart disease. Too much cholesterol may lead to fatty deposits in the blood vessels or arteries. These deposits, also known as plaque, can lead to atherosclerosis. This disease narrows your arteries, slowing down blood flow and reducing the amount of oxygenated blood that gets to your heart. This can result in a heart attack. If there is not enough oxygenated blood to the brain, you can have a stroke.
High cholesterol is hereditary in some cases. For most people, high cholesterol is the result of unhealthy lifestyle choices such as poor diet, little to no exercise, being overweight, and smoking. Medical conditions that are risk factors for high cholesterol are high blood pressure, and diabetes.
The Three Types of Cholesterol
Most people have head of “bad” cholesterol, also know as low-density lipoprotein (LDL).These proteins are small particles of cholesterol that flow through the arteries. The second type is called very-low-density lipoprotein (VLDL). This type of cholesterol has a large amount of triglycerides, a form of fat. VLDP increases the size of LDL cholesterol, clogging the walls of arteries and narrowing them so that less blood can circulate. The “good” cholesterol is high-density lipoprotein (HDL). HDL attaches itself to cholesterol and returns it to the liver, a filtering organ.
How Crestor Works
Crestor is a group of drugs called statins. These drugs reduce “bad” cholesterol by blocking an enzyme the liver needs to produce cholesterol. This enzyme is HMG-CoA reductase and it causes the liver to remove excessive levels of cholesterol from the bloodstream. Statins may also work by reabsorbing the cholesterol fatty deposits that line the artery walls.
Side Effects of Crestor
With any drug, there are side effects, and Crestor is no exception. One of the most serious side effects is an allergic reaction to the drug. Symptoms include difficulty breathing, swelling of the face, tongue or throat, or hives. You should see a doctor immediately if you have any of these problems.
There are many other symptoms you can experience while on Crestor. These include contradicting symptoms such as loss of appetite, hunger, weight loss, weight gain, increased urination, or urinating less. Other symptoms are nausea, weakness, stomach pain, fever, fruity breath smell, dry skin, dry mouth, blurred vision, yellowing of eyes or skin, muscle pain, dark urine, itching, confusion, and increased thirst.
MediGuard.org reports that 29% of Crestor users report having side effects. The most common side effect is muscle pain or cramps (16%). Other reported side effects are weakness (4%) and fatigue (3%). Less than 1% of patients experience side effects such as headache, back pain, constipation, weight gain, sleepiness, hyperglycemia, hair loss, and memory or speech problems.
The Use of Crestor
The Federal Drug Administration (FDA) approved the use of Crestor in August 2003. The drug is suitable for adults and children over the age of ten. Creator, manufactured by AstraZeneca Pharmaceuticals, is one of the most popular drugs prescribed by doctors. According to IMS Health, the drug ranks number five among all United States pharmaceuticals and had over $1.2 million in sales for the third quarter of 2013. Of the 32,000 patients in the study taking Creator and similar drugs, 73% are “somewhat satisfied” with the results of this drug, reports MediGuard.org.
The clinical trial Eclipse compared two statins drugs, Crestor and Lipitor. In the 24-week trial of over 1,000 high-risk patients, a far greater number of people reached their target goal of lower LDL while on Crestor than those who were on Lipitor, another statin drug.
Doctors need to run periodic blood tests on users to make certain that Crestor is working to lower LDL cholesterol without causing any harm to your body. The drug is not suitable for women who are pregnant or who are breast-feeding. Creator should also not be used by people with liver or kidney disease, or thyroid conditions. .
Crestor is often used in conjunction with a balanced diet, regular exercise and weight management. By establishing a healthier lifestyle, Crestor works better at lowering “bad” cholesterol in the blood.